Cellceutix Concludes Last Patient Visit in Phase 2 FDA Trial of Oral Dosed Prurisol in Patients with Mild-to-Moderate Chronic Placque Psoriasis

BEVERLY, MA–(Marketwired – March 17, 2016) - Cellceutix (OTC: CTIX) (the “Company”), a clinical stage biopharmaceutical company developing innovative therapies with oncology, dermatology, anti-inflammatory and antibiotic applications, is pleased to announce the conclusion of the last patient visit in its randomized, double-blind Phase 2 trial of orally-administered Prurisol for the treatment of mild to moderate chronic plaque psoriasis. The unblinding of the study and top-line data is expected to be available in May. Although the data is still blinded, there were no safety items of concern.

“We eagerly await the Phase 2 results for Prurisol, now less than two months away,” remarked Leo Ehrlich, Chief Executive Officer at Cellceutix. “We do significant laboratory research before engaging in a trial. That may be a reason why we have successfully completed three different studies on three very different compounds. The need for newer, non-biologic drugs, especially those that are easily-administered and well-tolerated for hard-to-treat psoriasis, is considerable. AbbVie’s recent $595 million deal with Boehringer demonstrates the level of interest among large pharmaceutical companies in novel psoriasis treatments. Outside of Celgene’s blockbuster Apremilast (Otezla), a drug expected to generate over $1 billion annually, only a handful of orally-administered drugs currently are in the pipeline for psoriasis. Prurisol is now one step closer to the goal line. We look forward to sharing the Prurisol trial results once they become known to us.”

More information about the Phase 2 Trial of Prurisol for Chronic Psoriasis:

https://clinicaltrials.gov/ct2/show?term=prurisol&rank=2

More information about Prurisol: Prurisol is a small molecule that acts through immune modulation and PRINS reduction and currently is being evaluated in a Phase 2 FDA trial under the U.S. Food and Drug Administration’s 505(b)(2) pathway, which can help expedite a drug’s approval by relying, in part, on clinical data from an already approved drug. In laboratory studies, Prurisol was found to be effective against psoriasis in animal models, both in induced psoriasis as well as in a xenograft model using human psoriatic tissue. Prurisol eliminated virtually all signs of psoriasis with no reoccurrence of the lesions. Prurisol is synthesized through a five-step process using commercially available starting materials.

http://cellceutix.com/prurisol/